Parkinson’s-linked gene mutations may drive iron buildup in brain cells
Disease-causing mutations in the LRRK2 gene may disrupt iron regulation and promote cell damage, potentially contributing to the loss of dopamine-producing nerve cells in Parkinson's disease, a study found. The findings suggest that abnormal LRRK2 protein activity may contribute to iron accumulation inside cells and promote oxidative stress and processes linked to ferroptosis, an iron-dependent […]
