Plos iconPlosSep 10, 2026

Analysis of multicellular anatomical structures from spatial omics data using sosta

We illustrate this type of analysis using two publicly available datasets and provide sosta, an open-source Bioconductor package for broad community use. Robinson Spatial omics technologies enable high-resolution, large-scale quantification of molecular features while preserving the spatial context within tissues.

Analysis of multicellular anatomical structures from spatial omics data using sosta

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Robinson Spatial omics technologies enable high-resolution, large-scale quantification of molecular features while preserving the spatial context within tissues.

Here, we introduce structure-based analysis of spatial omics data, which focuses on the direct analysis of multicellular, anatomical structures.

We illustrate this type of analysis using two publicly available datasets and provide sosta, an open-source Bioconductor package for broad community use.

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Robinson Spatial omics technologies enable high-resolution, large-scale quantification of molecular features while preserving the spatial context within tissues. Here, we introduce structure-based analysis of spatial omics data, which focuses on the direct analysis of multicellular, anatomical structures. We illustrate this type of analysis using two publicly available datasets and provide sosta, an open-source Bioconductor package for broad community use.

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