Lingering Senescent Cells in Aged Tissues Use PD-L2 to Evade Destruction by Immune Cells
PD-L1 and PD-L2 are components of immune checkpoints, widely expressed in tissues throughout the body. They act by binding to the PD-1 receptor on immune cells to suppress immune activation, and are part of the panoply of biochemical interactions that provide self-tolerance to prevent the immune system from inappropria
