Genetically predicted higher PFOA levels were inversely associated with IgA nephropathy (OR = 0.21, P = 0.004), but positively associated with hypertensive nephropathy (OR = 1.20, P
Genetically predicted higher PFOA levels were inversely associated with IgA nephropathy (OR = 0.21, P = 0.004), but positively associated with hypertensive nephropathy (OR = 1.20, P
by Dianjie Zeng, Yuxi Wang, Yinhuai Wang, Guoqiang Li, Wenpeng Wang, Zhongkun Zuo Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants with bioaccumulation potential, but their...
This study integrated Mendelian randomization and computational toxicology to examine associations between genetically predicted circulating PFAS levels and kidney disease outcomes and to prioritize...
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Genetically predicted higher PFOA levels were inversely associated with IgA nephropathy (OR = 0.21, P = 0.004), but positively associated with hypertensive nephropathy (OR = 1.20, P by Dianjie Zeng, Yuxi Wang, Yinhuai Wang, Guoqiang Li, Wenpeng Wang, Zhongkun Zuo Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants with bioaccumulation potential, but their associations with kidney diseases remain incompletely understood. This study integrated Mendelian randomization and computational toxicology to examine associations between genetically predicted circulating PFAS levels and kidney disease outcomes and to prioritize candidate toxicogenomic pathway themes.
by Dianjie Zeng, Yuxi Wang, Yinhuai Wang, Guoqiang Li, Wenpeng Wang, Zhongkun Zuo Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants with bioaccumulation potential, but their associations with kidney diseases remain incompletely understood.
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