Healio iconHealioSep 24, 2026

Nicotine increased complications after ankle fracture fixation

Patients who used nicotine within 1 year before open reduction and internal fixation for ankle fracture had an increased risk for postoperative complications, according to results. Results also showed patients who used both nicotine and cannabis within 1 year before open reduction and internal fixation had comparable complication rates to the nicotine-only group.

Nicotine increased complications after ankle fracture fixation

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Patients who used nicotine within 1 year before open reduction and internal fixation for ankle fracture had an increased risk for postoperative complications, according to results.

Results also showed patients who used both nicotine and cannabis within 1 year before open reduction and internal fixation had comparable complication rates to the nicotine-only group.

"Anytime people are using these substances, we have to give guidance on what the implications could be as far as outcomes, especially as it relates to medical and surgical complications," Amiethab Aiyer,...

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Patients who used nicotine within 1 year before open reduction and internal fixation for ankle fracture had an increased risk for postoperative complications, according to results. Results also showed patients who used both nicotine and cannabis within 1 year before open reduction and internal fixation had comparable complication rates to the nicotine-only group. "Anytime people are using these substances, we have to give guidance on what the implications could be as far as outcomes, especially as it relates to medical and surgical complications," Amiethab Aiyer, MD, FAOA, FAAOS,

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