NAD+ Collapse Drives Senescent CD8+ T Cells That Worsen Ulcerative Colitis
Ulcerative colitis has long been framed as a disease of overactive immunity, a condition in which the immune system attacks the lining of the colon with unrelenting ferocity. Most existing therapies, from corticosteroids to modern biologics, are built on that premise: they try to dampen T cell activation or block the r
