Integrating zero-inflation correction and transcriptional kinetics for single-cell transcriptomic analysis
by Chengkai Yang, Yu Liao, Ying Sheng, Feng Jiao Single-cell transcriptomic data exhibit pervasive zero inflation, while traditional models either neglect this issue or fail to capture transcriptional burst-driven bimodality, hindering accurate gene regulatory studies. This study developed a zero-inflated telegraph mod