Science Daily iconScience DailySep 27, 2026

Why rheumatoid arthritis pain may persist even when inflammation is under control

Pain and fatigue in rheumatoid arthritis can persist even after inflammation improves, with depression, poor sleep, obesity, smoking, and chronic pain potentially helping sustain symptoms. Researchers say identifying these hidden drivers could prevent unnecessary medication changes and lead to more personalized treatment.

Why rheumatoid arthritis pain may persist even when inflammation is under control

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Pain and fatigue in rheumatoid arthritis can persist even after inflammation improves, with depression, poor sleep, obesity, smoking, and chronic pain potentially helping sustain symptoms.

Researchers say identifying these hidden drivers could prevent unnecessary medication changes and lead to more personalized treatment.

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Pain and fatigue in rheumatoid arthritis can persist even after inflammation improves, with depression, poor sleep, obesity, smoking, and chronic pain potentially helping sustain symptoms. Researchers say identifying these hidden drivers could prevent unnecessary medication changes and lead to more personalized treatment.

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