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Do you buy the idea of using in vivo reprogramming to fight aging? How about to treat certain diseases? The stream of research pubs and news articles continues to grow. Before we jump into weekly reads including on reprogramming applications, on the 20th anniversary of iPS cells, enter our $200 stem cell contest. Repro
There is growing concern about unproven regenerative clinics getting out of control in Japan. Some clinic customers have died there. More have experienced adverse events. Some of this is traceable to Japan’s unique regenerative medicine oversight system. For these reasons, Japan is facing a regulatory crossroads on reg
Karim Mikhail, acting CBER director, has just been named the permanent branch leader. What might this mean for the cell and gene therapy field? Karim Mikhail is permanent CBER director, unusual background Most people in the field want more stability and logic-based decision-making. For instance, if CBER is going to be
Anyone out there use a peptide cream? You might not even know it. I just saw by accident that one of the family uses a shampoo that says “peptides” on it. If you search on Amazon for “peptide cream” you get about an infinite number of results. Peptides in shampoos and creams are probably mostly […] The post Weekly read
I’ve followed a stem cell clinic firm called R3 Stem Cell for years and have had concerns about its practices. There are many R3 Stem Cell clinics both inside and outside the US. In my opinion, at times they seemed to be marketing unproven regenerative cell offerings. Based on past FDA actions and statements, some […]
Depending on who you ask, aging clocks might be the best thing since sliced bread or still relatively imprecise tools that aren’t ready for prime time use for healthcare of any kind. I fall somewhere in the middle. These clocks are getting better and they provide some predictive value, but probably much less than the [
I’ve been debating whether to unfollow longevity enthusiasts David Sinclair and Bryan Johnson on X. I find their posts about various anti-aging efforts to be fascinating on one level but also very unsettling. For one thing, some posts seem close to medical advice to the public, yet neither is a physician. The statement
I have to admit to loving just about everything related to iPS cells. If you love them or other pluripotent stem cells enough, you might win $200. Maybe the clearest sign of my focus on iPS cells is this website’s URL, ipscell.com. In a way, it’s hard to believe it was 20 years ago that […] The post Celebrating 20 year
After many years bouncing around the courts, today the FDA finally prevailed in getting a permanent injunction against a chain of stem cell clinics, Cell Surgical Network, and its flagship clinic California Stem Cell Treatment Center as well as its remaining leader, Dr. Elliot Lander on use of an adipose cell preparati
The question of the week might be: who is Heidi Overton? I’ve been wondering who the new FDA commissioner might be for months. Marty Makary, Vinay Prasad, and Tracy Hoeg all left in the spring. There’s a big leadership vacuum at the agency. FDA commissioner nomination soon? White House policy official and physician-sci
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