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For ophthalmologists, occupational pain can start early. For Cynthia Matossian, MD, FACS, discomfort arose fewer than 5 years into her career. She said surgeons often find themselves in similar positions over the course of their routine work, and repeated motions can wear people down. “There were two areas that I notic
NASHVILLE, Tenn. — Body roundness index may improve mortality risk stratification in metabolic dysfunction-associated steatotic liver disease, identifying high-risk lean and nonobese individuals often overlooked by BMI. Findings presented at ACG Annual Scientific Meeting indicated that, although BMI remains a useful me
NASHVILLE, Tenn. — Tezepelumab significantly improved histologic remission and dysphagia symptoms at 24 and 52 weeks compared with placebo among individuals with eosinophilic esophagitis, according to a presenter. Thymic stromal lymphopoietin (TSLP), an antibody, is associated with EoE pathogenesis. “Food allergens and
Clinician counseling may be inadequate for younger adults newly eligible for colorectal cancer screening, according to study findings presented at this year’s AACR Conference on The Science of Cancer Health Disparities. A survey of screening-eligible individuals in the U.S. showed those aged 45 to 49 years were approxi
NASHVILLE, Tenn. — Antidrug antibodies did not appear to negatively affect outcomes in patients with inflammatory bowel disease after initiation of subcutaneous infliximab following a “drug holiday,” according to a presenter. Results of a post-hoc analysis presented at ACG Annual Scientific Meeting also showed serum in
The FDA approved bepirovirsen as the first antisense oligonucleotide for chronic hepatitis B virus infection, alongside existing antiviral therapy for eligible adults without cirrhosis. Bepirovirsen (Hibsago, GSK) is indicated for adults who have taken HBV antiviral therapy for at least 6 months, have suppressed levels
WASHINGTON — A new retrospective cohort study revealed that more than half of early childhood exposures to hepatitis B virus come from household members other than the birth mother. Researcher Karen B. Jacobson, MD, MPH, said the study’s shows that delaying HBV vaccination based strictly on maternal status puts infants
NASHVILLE, Tenn. — Investigational oral interleukin-23 inhibitor icotrokinra sustained efficacy and favorable tolerability through week 76 in patients with moderately to severely active ulcerative colitis, according to data presented here. Findings from a long-term extension of the phase 2b ANTHEM-UC trial, presented a
NASHVILLE, Tenn. — Among children with ulcerative colitis, mirikizumab achieved clinical and endoscopic remission rates exceeding those of historical adult outcomes with placebo at week 12, according to data presented. Researchers also reported associations between mirikizumab (Omvoh, Eli Lilly & Co.) and clinical, sym
PHOENIX — Adults with asthma who used proton pump inhibitors had greater risks for exacerbations and other negative outcomes than those who did not, according to an abstract presented at the CHEST Annual Meeting. However, the difference in mortality between patients who did or did not use proton pump inhibitors (PPIs)
NASHVILLE, Tenn. — An updated version of the blood-based SimpleScreen CRC screening test improved detection of advanced precancerous lesions while maintaining high sensitivity for colorectal cancer in an average-risk adult population. Data presented at ACG Annual Scientific Meeting showed the largest improvement in sen
NASHVILLE, Tenn — Fecal immunochemical tests appear more sensitive to colorectal cancer and advanced precancerous lesions in men than women, according to a retrospective study presented at ACG Annual Scientific Meeting. “FIT is the most commonly used colorectal cancer screening test in the world, with an average sensit
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