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by Nazia Thakur, Joseph Newman, Dongchun Ni, Jeffrey Seow, Abigail L. Hay, Yeonjae Lee, Ayush Upadhyay, Babatunde E. Ekundayo, John A. Hammond, Thomas P. Peacock, Kelvin Lau, Katie J. Doores, Dalan Bailey Sarbecoviruses interact with their receptor, angiotensin-converting enzyme 2 (ACE2), via the receptor-binding domai
by Ayush Upadhyay, Jeffrey Seow, Yilmaz Alguel, Joseph Newman, Nazia Thakur, Abigail L. Hay, Jerry C. H. Tam, Andrea Nans, Richard J. Orton, Dalan Bailey, Peter Cherepanov, Katie J. Doores The continuing evolution of SARS-CoV-2 variants of concern, and the increasing spillover potential of sarbecoviruses into the human
by Noora Poikela, Rhonda R. Snook, Jonna Kulmuni, Michael G. Ritchie As global temperatures rise and heat waves become more frequent, populations must adapt rapidly to avoid local extinctions. Adaptive introgression allows species to quickly acquire adaptive genetic material from close relatives. However, certain genom
by L. Christoffer Johansson, Gabriel Norevik, Sonja Friman, Anders Hedenström The European nightjar ( Caprimulgus europaeus ) is a long-distance migrant that also uses slow, hovering, flight as part of its feeding ecology. This reflects complex tradeoffs in aerodynamic mechanisms and makes studies of their flight perfo
by Jie Ren, Yu Sang, Young-Mo Kim, Ernesto S. Nakayasu, Alejandro Aballay Animals must allocate limited energetic resources across competing defense programs in response to infection. Here, we show that the conserved nuclear hormone receptor NHR-68 integrates fatty acid metabolism with the neural control of molecular a
by Shannon Esher Righi Fungal biofilm formation has long been considered an important virulence trait. A new study on Candida parapsilosis outbreak isolates in PLOS Biology challenges this, finding that low biofilm-producing strains are better adapted for immune evasion and survival. Fungal biofilm formation has long b
by Golia Shafiei, Joëlle Bagautdinova, Valerie J. Sydnor, Dani S. Bassett, Deanna M. Barch, Matthew Cieslak, Yong Fan, Elizabeth Flook, Alexandre R. Franco, Gregory Kiar, Audrey C. Luo, Michael P. Milham, Linden Parkes, Taylor Salo, Leah H. Somerville, Tien T. Tong, Russell T. Shinohara, Theodore D. Satterthwaite Intri
by Hsiao-Yuh Roan, Xuejiao Tian, Wei-Chen Chu, Chia-Ming Lee, Hsin Chen, Fiorency Santoso, Chung-Han Wang, Yu-Hsiu Liu, Uday Kumar, He-Yun Hsiao, Chiou-Hwa Yuh, Bi-Chang Chen, Chen-Hui Chen Vertebrate organs undergo massive growth during the post-embryonic period. Yet, our understanding of how this organ-wide process i
by Amanda A. G. Ferreira, Sergio Córdoba, Raghuvanshi Rajesh, Ben Jiwon Choi, Claude Desplan Glial cells are essential for proper nervous system development and function. To understand glial development and function, we comprehensively annotated the glial cells from two large single-cell mRNA-sequencing (scRNA-seq) atl
by Katrine E. Dailey, Yiquan Wang, Qi Wen Teo, Chaoyang Wang, Huibin Lv, Ruipeng Lei, Meixuan Tong, Lucia A. Rodriguez, Letianchu Wang, Nicholas C. Wu The highly conserved influenza virus hemagglutinin (HA) stem domain is a major target for broadly neutralizing antibodies (bnAbs). However, despite being discovered more
by Bradley C. Allf, Aditi Mallavarapu, David W. Kikuchi, Nikhil Vasudeva, Robert R. Dunn Citizen science contains abundant yet underutilized data about species interactions. We present Who Eats Whom, a database and public engagement tool for searching and visualizing thousands of feeding relationships derived from iNat
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